Whole-Exome Sequencing Reveals High Mutational Concordance between Primary and Matched Recurrent Triple-Negative Breast Cancers.

Jaspreet Kaur,Darshan S Chandrashekar,Zsuzsanna Varga,Bettina Sobottka,Emiel Janssen,Khanjan Gandhi,Jeanne Kowalski,Umay Kiraz,Sooryanarayana Varambally,Ritu Aneja

Genes（2023）

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摘要

We found similar mutational profiles between primary and paired recurrent tumors, suggesting that genomic features may be retained during local recurrence.

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关键词

triple negative breast cancer, tumor mutational burden, whole exome sequencing

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