Hydrogel Assisted Synthesis of Polymeric Materials Based on Chitosan, Oxidized Pectin, and Tantalum MOF Nanostructures as Potent Antibiotic Agents Against Common Pathogenic Strains Between Humans and Aquatic

The synthesis of polymers using environmentally friendly materials is on the rise. New chitosan, oxidized pectin, and tantalum metal–organic framework hydrogel were synthesized using chitosan and pectin, which are both available and environmentally friendly polymer materials. By scanning electron microscope images, energy-dispersive X-ray spectroscopy and EDAX mapping, X-ray diffraction pattern, Fourier transform infrared spectrum, and N 2 adsorption/desorption isotherm curve, the structure of the synthesized polymer was confirmed. A specific surface area of about 26 m 2 /g was observed from the final system. The same morphology, and 51 nm particle size were other features of synthetic chitosan, oxidized pectin, and tantalum metal–organic framework hydrogel. The antimicrobial activity of the synthesized polymer was studied on Yersinia ruckeri, Vibrio fluvialis, Edwardsiella tarda, Lactococcus garvieae , and Streptococcus iniae as microbial agents of aquatic pathogens. The synthetic polymer studied in this research can be reported as a robust antimicrobial compound with an MBC of 4–128 mg/ml. A key aspect of this study is the synthesis of new polymers using environmentally friendly and controllable methods. Among other novelties of this study, it can be mentioned that it is effective against common pathogenic strains of humans and aquatic, which in some cases was more effective than available commercial drugs.