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Long Noncoding RNA TALAM1 Is a Transcriptional Target of the RUNX2 Transcription Factor in Lung Adenocarcinoma.

Gisella Bermúdez,Camila Bernal,Andrea Otalora,Paula Sanchez,Gino Nardocci,Alejandra Cañas,Liliana Lopez-Kleine,Martín Montecino,Adriana Rojas

Current issues in molecular biology（2023）

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Abstract
We observed RUNX2 overexpression in cell lines and primary cultured lung cancer cells. Interestingly, we found that lncRNA TALAM1 was a target of RUNX2 and that RUNX2 exerted a negative regulatory effect on transcription.
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Key words
lung cancer,RUNX2,TALAM1,ChIP-seq
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