Topical dexpanthenol effects on physiological parameters of the stratum corneum by Confocal Raman Microspectroscopy.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)（2023）
Abstract
Effects of topical dexpanthenol on SC suggest a contribution in increasing fluidity of both lipidic and protein components of the SC and are compatible with dexpanthenol activity in maintaining adequate physiological conditions and preventing transepidermal water loss. This study also contributes to the elucidation of action mechanisms and other concurrent biochemical processes.
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Key words
dexpanthenol, intercellular lipids, natural moisturizing factor, skin barrier function
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