Interferences by factor VIII and lupus anticoagulant in the modified one-stage assay for emicizumab.

HaemophiliaEarly View LETTER TO THE EDITOR Interferences by factor VIII and lupus anticoagulant in the modified one-stage assay for emicizumab Capucine Habay, Capucine Habay Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorClaire Auditeau, Claire Auditeau orcid.org/0000-0002-8499-1862 Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorAdeline Blandinières, Adeline Blandinières orcid.org/0000-0001-5285-9165 Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorNûn K Bentounes, Nûn K Bentounes Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorCécile Lavenu-Bombled, Cécile Lavenu-Bombled Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorAnnie Harroche, Annie Harroche orcid.org/0000-0001-7368-4624 Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorCecile Bally, Cecile Bally Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorLaurent Frenzel, Laurent Frenzel orcid.org/0000-0002-6085-2163 Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorDelphine Borgel, Delphine Borgel Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorDominique Lasne, Corresponding Author Dominique Lasne [email protected] orcid.org/0000-0001-6600-0263 Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Correspondence Dominique Lasne, Laboratoire d'Hématologie générale, AP-HP, 149 rue de Sèvres, Hôpital Necker Enfants Malades, F-75015 Paris, France. Email: [email protected]Search for more papers by this author Capucine Habay, Capucine Habay Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorClaire Auditeau, Claire Auditeau orcid.org/0000-0002-8499-1862 Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorAdeline Blandinières, Adeline Blandinières orcid.org/0000-0001-5285-9165 Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorNûn K Bentounes, Nûn K Bentounes Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorCécile Lavenu-Bombled, Cécile Lavenu-Bombled Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorAnnie Harroche, Annie Harroche orcid.org/0000-0001-7368-4624 Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorCecile Bally, Cecile Bally Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorLaurent Frenzel, Laurent Frenzel orcid.org/0000-0002-6085-2163 Centre de Traitement de l'Hémophilie, AP-HP, Hôpital Necker Enfants Malades, Paris, FranceSearch for more papers by this authorDelphine Borgel, Delphine Borgel Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, FranceSearch for more papers by this authorDominique Lasne, Corresponding Author Dominique Lasne [email protected] orcid.org/0000-0001-6600-0263 Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France Université Paris-Saclay, INSERM, Hémostase inflammation thrombose HITh U1176, Le Kremlin-Bicêtre, France Correspondence Dominique Lasne, Laboratoire d'Hématologie générale, AP-HP, 149 rue de Sèvres, Hôpital Necker Enfants Malades, F-75015 Paris, France. Email: [email protected]Search for more papers by this author First published: 25 September 2023 https://doi.org/10.1111/hae.14873Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1Oldenburg J, Mahlangu JN, Kim B, et al. Emicizumab prophylaxis in Hemophilia A with inhibitors. N Engl J Med. 2017; 377(9): 809-818. 2Nougier C, Jeanpierre E, Ternisien C, et al. Emicizumab treatment: impact on coagulation tests and biological monitoring of haemostasis according to clinical situations (BIMHO group proposals). Eur J Haematol. 2020; 105(6): 675-681. 3Adamkewicz JI, Chen DC, Paz-Priel I. Effects and interferences of emicizumab, a humanised bispecific antibody mimicking activated Factor VIII cofactor function, on coagulation assays. Thromb Haemost. 2019; 119(07): 1084-1093. 4Susen S, Gruel Y, Godier A, et al. Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra ®): proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in collaboration with the French Working Group on Perioperative Haemostasis (GIHP). Haemophilia. 2019; 25(5): 731-737. 5Miller CH, Boylan B, Payne AB, Driggers J, Bean CJ. Validation of the chromogenic Bethesda assay for factor VIII inhibitors in hemophilia a patients receiving Emicizumab. 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Emicizumab assays evaluations with four different reagents in severe haemophilia A patients: concentration from baseline to maintenance therapy. Haemophilia. 2023; 29(1): 374-376. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation