Dosimetric and radiobiological comparison between conventional and hypofractionated breast treatment plans using the Halcyon system.

Duong Thanh Tai, Luong Tien Phat,Nguyen Ngoc Anh, Huynh Van Tran Sang, Tran Minh Loc,Nguyen Xuan Hai,Peter A Sandwall,David Bradley,James C L Chow

Frontiers in Oncology（2023）

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Abstract

The analysis suggests that while the CF plan is better at controlling tumors, it is not as effective as the HF plan in minimizing side effects. Additionally, it is suggested that there may be an optimal configuration for the HF plan that can provide the same or higher EUD than the CF plan.

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Key words

radiotherapy treatment plan, conventional fractionated (CF), hypofractionated (HF), breast cancer, radiobiology model, Halcyon, normal tissue complication probability (NTCP), tumor control probability (TCP)

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