Confirmation of the structure of (±)-preisomide by total synthesis.

Hong Kang Teo, Patcharaporn Sae-Lao,Roderick W Bates

Organic & biomolecular chemistry(2023)

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摘要
The structure of preisomide has been confirmed by total synthesis involving chemoselective oxazine formation and vinyl iodide carbonylation in six steps (longest linear sequence) and 23% overall yield.
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total synthesis
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