OLIG2 translocates to chromosomes during mitosis via a temperature downshift: A novel neural cold response of mitotic bookmarking.

Shinichi Hayashi,Ryohei Seki-Omura,Shintaro Yamada,Taito Kamata, Yuki Sato,Souichi Oe,Taro Koike,Yousuke Nakano,Hikaru Iwashita,Yukie Hirahara,Susumu Tanaka,Tsuneo Sekijima,Takeshi Ito,Yoshiki Yasukochi,Koichiro Higasa,Masaaki Kitada

Gene（2023）

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摘要

•OLIG2 translocates to chromosomes during mitosis by a temperature downshift.•Transcriptome of cold-inducible OLIG2 cell lines highlighted Phox2b expression.•PHOX2B is located on a chromosome and facilitates OLIG2 bookmarking during mitosis.•OLIG2 provide insights into mammalian cold adaptation and neuroprotection.

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