A nanohybrid of Fe3O4/SnO magnetic recyclable catalyst for chemoselective N1-acylation of sulfanilamide under mild reaction conditions

In this article, an effective heterogeneous catalytic system was developed for selective N-acylation of pharmaceutical intermediate. The catalyst is a binary compound composed of Fe3O4-wrapped stannous oxide nanoparticles with magnetic separation capability. The prepared catalyst was used for selective N-acylation of sulfanilamide using acetic anhydride under mild reaction conditions without protecting the NH2 group. The best results of 85