Identification of γ-Fagarine as a novel antiviral agent against respiratory virus (hMPV) infection
Virus Research(2023)
摘要
•γ-Fagarine possesses inhibitory activity against human metapneumovirus (hMPV) in vitro and in vivo.•γ-Fagarine blocking hMPV binding and infection relates to heparan sulfate proteoglycans.•γ-Fagarine influences the lysosome pH to inhibit virus replication.
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关键词
γ-Fagarine,hMPV,Antiviral activity,Lysosome,HSPG
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