Which are the best murine models to study Eosinophilic Chronic Rhinosinusitis? A contemporary review

Francisco Leite-Santos,Edwin Tamashiro,Adriana de Andrade Batista Murashima,Wilma T. Anselmo-Lima,Fabiana C.P. Valera

Brazilian journal of otorhinolaryngology（2023）

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摘要

•BALB/c mice seem to produce a more robust eosinophilic response than C57BL/6 mice.•OVA and SEB protocol was the one that most resembled to ECRS.•OVA and AP protocol also induced inflammation similar to ECRS, but to a lesser extent.

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关键词

Chronic rhinosinusitis,Eosinophilic rhinosinusitis,Mouse,Nasal polyps,Staphylococcus aureus,Aspergillus oryzae protease

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