Development of cyclosporine-induced linear IgA bullous dermatosis despite concurrent use of dapsone

Linear IgA bullous dermatosis (LABD) is a rare subepidermal-blistering disease caused by antibasement membrane IgA antibodies. The exact pathogenesis of LABD remains unknown. In adults, LABD is typically caused by antibiotics, such as vancomycin, penicillins, cephalosporins, and sulfonamides.1 Antihypertensives, antiepileptics, analgesics, and immunosuppressive medications, such as cyclosporine, have also been implicated.2 The first step in management is withdrawal of the causative agent. The first-line therapeutic agent is dapsone, and improvement is often seen within days of starting treatment.