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Intrinsic resistance to ROS1 inhibition in a patient with CD74-ROS1 mediated by AXL overexpression.

Tara L Peters,Nan Chen,Logan C Tyler,Anh T Le,Anastasios Dimou,Robert C Doebele

Thoracic cancer（2023）

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Abstract
In summary, we demonstrate that AXL overexpression is a mechanism of intrinsic resistance to ROS1 inhibitors.
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Key words
AXL,drug resistance,NSCLC,ROS1
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