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Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia.

Shiyu He,Jinxia Zhao,Jialu Bian,Yinyu Zhao,Yuanyuan Li,Nan Guo,Lei Hu,Boyu Liu,Qianhang Shao, Huan He,Lin Huang,Qian Jiang

Pharmaceutical research（2023）

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Abstract
This study's findings suggested that low-dose dasatinib would be better suited for Chinese patients, and the dosage can be appropriately reduced according to the increase of age, especially for the elderly.
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Key words
chronic myeloid leukemia, dasatinib, individualized medicine, pharmacogenetics, population pharmacokinetics
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