Protein C and protein S deficiencies are associated with increased risk of deep vein thrombosis in pregnant women using oral contraceptives.

Elyasa M Elfaki,Abdulrahman Algarni,Tagwa Yousif Elsayed Yousif,Alneil Hamza,Ezeldine K Abdalhabib,Husham O Elzein,Eldaw M Habiballah,Osama A B Ahmed,Hussam Ali Osman,Praveen Kumar,Asaad M A Babker,Ayman H Alfeel,Muhammad Saboor

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis（2023）

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摘要

This study suggests that the use of contraceptives, particularly those containing Desogestrel, Norgestimate, and Gestodene, may be associated with a higher risk of thrombosis because of the associated lower levels of PS. Monitoring anticoagulant levels is crucial in preventing DVT in this population.

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antithrombin, deep vein thrombosis, oral contraceptives, protein C, protein S

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