Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.

Glaivy Batsuli,Jasmine Ito,Elizabeth S York,Courtney Cox,Wallace Baldwin,Surinder Gill,Pete Lollar,Shannon L Meeks

Frontiers in immunology（2023）

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摘要

These findings suggest that a subset of FVIII-IC modulates the humoral response to FVIII in an epitope-dependent manner, which may provide insight into the antibody response observed in some patients with hemophilia A.

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关键词

factor viii antibody,factor viii,immune complexes,epitope-dependent

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