The role of galectin-3 in patients with permanent and paroxysmal Atrial Fibrillation and echocardiographic parameters of left atrial fibrosis.

Maria Mariana Barros Melo da Silveira,João Victor Batista Cabral,Amanda Tavares Xavier,Kleyton Palmeira do Ó,Julio Francisco de Moura Junior,Osmário Tavares de Carvalho,Edivaldo Bezerra Mendes Filho,Taciana Furtado de Mendonça Belmont,José Maria Del Castillo,Moacyr Jesus Barreto de Melo Rêgo,Luydson Richardson da Silva Vasconcelos,Dário Celestino Sobral Filho,Dinaldo Cavalcanti de Oliveira

Molecular biology reports（2023）

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摘要

Echocardiographic findings showed association with the groups, and with serum levels of Gal-3 in patients with permanent AF. The distribution of allelic and genotypic frequencies, and of the haplotypes of polymorphism LGALS3 rs4652 and rs4644 did not present statistical variation, which suggests that those SNPs are not associated with the AF clinical forms (permanent and paroxysmal).

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关键词

Atrial fibrillation, Atrial fibrosis, Galectin-3, Speckle-tracking echocardiography, Genetic polymorphism

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