Genetic variants of metabolism and inflammatory pathways, and PCOS risk –Systematic review, meta-analysis, and in-silico analysis

Priya Sharma, Kabir Bhatia,Harmanpreet Singh Kapoor,Balpreet Kaur,Preeti Khetarpal

Gene（2023）

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摘要

•Metabolic genetic variants FTO rs9939609 and IL-6 rs1800795 increase the risk of PCOS.•CAPN10 rs3842570 decrease risk; CAPN10rs2975760 and RAB5B rs705702 increase risk.•No association for CAPN10 rs3792267, rs5030952, and SUMO1P1 rs2272046 for PCOS risk.

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关键词

Genetic variant,Inflammation,Meta-analysis,Metabolism,Pathway,PCOS

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