Cancer- and infection-induced T cell exhaustion are distinct
Nature immunology（2023）
摘要
The transcription factor NFAT5 regulates T cell exhaustion, a dysfunctional state caused by chronic exposure to antigen and other signals, during cancer but not during chronic viral infection.
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关键词
CD8-positive T cells,Gene regulation in immune cells,Lymphocyte differentiation,Tumour immunology,Biomedicine,general,Immunology,Infectious Diseases
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