New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March-May 2023

Mike J. Mwanga,Arnold W. Lambisia,John Mwita Morobe,Nickson Murunga, Edidah Moraa,Leonard Ndwiga,Robinson Cheruiyot,Jennifer Musyoki,Martin Mutunga,Laura M. Guzman-Rincon,Charles Sande,Joseph Mwangangi,Philip Bejon,Lynette Isabella Ochola-Oyier,D. James Nokes,Charles N. Agoti,Joyce Nyiro,George Githinji

EMERGING INFECTIOUS DISEASES（2023）

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摘要

We report a newly emerged SARS-CoV-2 Omicron sub variant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April-May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify new lineages to inform COVID-19 outbreak prevention.

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spike protein mutation y451h,sars-cov,march-may

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