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CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma.

Karen L Burger, Mario R Fernandez, Mark B Meads, Praneeth Sudalagunta, Paula S Oliveira, Rafael Renatino Canevarolo, Raghunandan Reddy Alugubelli, Alexandre Tungsevik, Gabe De Avila, Maria Silva, Allison I Graeter, Hongyue A Dai, Nicole D Vincelette, Antony Prabhu, Dario Magaletti, Chunying Yang, Weimin Li, Amit Kulkarni, Oliver Hampton, John M Koomen, William R Roush, Andrii Monastyrskyi, Anders E Berglund, Ariosto S Silva, John L Cleveland, Kenneth H Shain

Cancer research（2023）

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Abstract
CK1δ and CK1ε are attractive therapeutic targets in multiple myeloma whose expression increases with disease progression and connote poor outcomes, and that are necessary to sustain expression of genes directing OxPhos.
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International Myeloma Working Group
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