SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile.
Genome medicine(2023)
摘要
SARS-CoV-2 infection causes a prolonged increase in the pro-inflammatory transcriptional status that could predispose post-acute patients to the development of long-term health consequences, including autoimmune disease, reactivation of other viruses and disruption of the host immune system-microbiome ecosystem.
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关键词
COVID-19,SARS-CoV-2,Post-acute sequelae of COVID-19 (PASC),IL-2-induced anti-inflammatory signature,NF-kB,Single-cell multiomics
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