Donor Lymphocyte Infusion for Prophylaxis and Treatment of Relapse in Pediatric Hematologic Malignancies after Allogeneic Hematopoietic Stem Cell Transplant.

Patients' disease status before HSCT and DLI may help predict EFS. The use of DLI as a prophylactic and preemptive modality leads to a favorable 5-year EFS. To safely deliver DLI in children, clinicians must maintain vigilant monitoring and prepare patients in advance when escalating the dose to ≥5 × 10 7 CD3 + cells/kg.