Mtb-induced Monocyte Transcriptional Responses Associate with Resistance to TST/IGRA Conversion in PLWH.

Hyejeong Hong,Kimberly A Dill-Mcfarland,Basilin Benson,Jason D Simmons,Glenna J Peterson,Penelope Bencheck,Catherine M Stein,W Henry Boom,Harriet Mayanja-Kizza,Thomas R Hawn

AIDS (London, England)（2023）

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摘要

RSTR monocytes in PLWH show different gene expression in response to Mtb infection when compared to those with LTBI and RSTR without HIV. These differential expression patterns are enriched in inflammatory pathways.

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