Preparation of acid-responsive antibubbles from CaCO3-based Pickering emulsions

Hypothesis: Hydrophobized fumed silica particles were previously reported for producing antibubbles that are quite stable in neutral as well as in acidic media. To produce acid-responsive antibubbles (e.g., for gastric drug delivery), the silica nanoparticles must be replaced by suitable particles, e.g., calcium carbonate (CaCO3), which can degrade at low pH to release the encapsulated drug.