The efficacy of buprenorphine on moderate traumatic brain injury in the rat model.

Hamid Reza Rasouli, Mehdi Mohammadian Salim,Samira Talebi,Mohammad Eslamian,Fathollah Ahmadpour

Neurological research（2023）

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摘要

These results suggest that buprenorphine causes fewer changes in behavioral functions in rats' models of mTBI and, because of their positive effect changes on inflammation biomarkers, biochemical behavioral tests, and CT scan images, could be ideal analgesic agents for pre-clinical responses after TBI.

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关键词

Trauma brain injury, buprenorphine, cortisol, prolactin, inflammation

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