COVID-19 vaccine booster doses provide increased protection against COVID-19 hospitalization compared with previously vaccinated individuals: Interim findings from the REFORCO-Brazil real-world effectiveness study during Delta and Omicron

Wilhelmine Meeraus,Anke L. Stuurman, Ilgaz Durukal,Eduardo Conde-Sousa,Andrew Lee, André Santa Maria, Bárbara Emoingt Furtado,Mario Ouwens,Christen M. Gray, Douglas Andreas Valverde, Hugo Gomes da Silva,Sylvia Taylor

Vaccine（2023）

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摘要

•rVEs show increased protection in eligible people receiving (vs not) a booster dose.•Overall rVE of any 2nd booster against COVID-19 hospitalization was 24.7 %.•rVEs were similar with 2nd booster doses of AZD1222 (29.4 %) and BNT162b2 (25.5 %).•rVE of any 1st booster vs having only received a primary series was 46.8 %.•The rVEs of 1st boosters of AZD1222 (42.5 %) and BNT162b2 (50.8 %) were similar.

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关键词

COVID-19,First booster,Hospitalisation,Omicron,Relative vaccine effectiveness,Second booster

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