COVID-19 vaccine booster doses provide increased protection against COVID-19 hospitalization compared with previously vaccinated individuals: Interim findings from the REFORCO-Brazil real-world effectiveness study during Delta and Omicron
Vaccine(2023)
Abstract
•rVEs show increased protection in eligible people receiving (vs not) a booster dose.•Overall rVE of any 2nd booster against COVID-19 hospitalization was 24.7 %.•rVEs were similar with 2nd booster doses of AZD1222 (29.4 %) and BNT162b2 (25.5 %).•rVE of any 1st booster vs having only received a primary series was 46.8 %.•The rVEs of 1st boosters of AZD1222 (42.5 %) and BNT162b2 (50.8 %) were similar.
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Key words
COVID-19,First booster,Hospitalisation,Omicron,Relative vaccine effectiveness,Second booster
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