Pharmacogenetics of tuberculosis treatment toxicity and effectiveness in a large Brazilian cohort.

Gustavo Amorim, James Jaworski,Marcelo Cordeiro-Santos,Afrânio L Kritski,Marina C Figueiredo,Megan Turner,Bruno B Andrade,Digna R Velez Edwards,Adalberto R Santos,Valeria C Rolla,Timothy R Sterling,David W Haas

medRxiv : the preprint server for health sciences（2023）

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摘要

In a clinical cohort representing three regions of Brazil, acetylator status was associated with risk for treatment-related adverse events. Additional significant polymorphisms merit investigation in larger study populations.

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