Agomelatine enhances the therapeutic effect of venlafaxine on depression and improves the levels of S100B and GFAP.

Jiali Zheng, Qian Zhao, Yani Ma, Jing Tian, Liangliang Sun, Zongyan Zhang, Long Guo

American journal of translational research（2023）

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摘要

S100B and GFAP can be used as diagnostic indicators of depression. Agomelatine plus venlafaxine are superior to venlafaxine alone in the treatment of depression. The combination can contribute to better S100B and GFAP levels, and take a more obvious role in alleviating disease symptoms, thereby improving the cognitive function and overall well-being of patients.

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关键词

Venlafaxine, agomelatine, depression, efficacy, S100B, GFAP

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