Renin-angiotensin system inhibitors reduce cardiovascular mortality in hypertensive patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: insights from the EffecTAVI registry.

Christian Basile,Costantino Mancusi,Anna Franzone,Marisa Avvedimento,Luca Bardi,Domenico Angellotti,Domenico Simone Castiello,Andrea Mariani,Rachele Manzo,Nicola De Luca,Plinio Cirillo,Giovanni De Simone,Giovanni Esposito

Frontiers in cardiovascular medicine（2023）

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摘要

In a cohort of hypertensive patients with severe AS who were selected from the EffecTAVI registry, ACEI/ARB treatment at baseline was found to be independently associated with a lower risk of 2-year cardiovascular mortality, suggesting a potential benefit of this treatment. More trials are needed to validate this finding and to understand the full benefit of this treatment.

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renin–angiotensin system inhibitors,severe aortic stenosis,aortic valve implantation,hypertensive patients

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