A protocol of a single arm, prospective, open-label, multicenter, phase II study of ramucirumab and erlotinib in treatment-naïve non-small cell lung cancer patients with EGFR mutation and brain metastases (SPIRAL-BRAIN study).

Ryo Sawada,Naoya Nishioka,Young Hak Kim,Fumiaki Kiyomi,Junji Uchino,Koichi Takayama

Translational lung cancer research（2023）

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摘要

Japan Registry of Clinical Trials, jRCTs051220059.

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Non-small cell lung cancer (NSCLC), epidermal growth factor receptor mutation (EGFR mutation), epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), brain metastasis, vascular endothelial growth factor or vascular endothelial growth factor receptor inhibitor (VEGF or VEGFR inhibitor)

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