Changes in Peripheral Blood Eosinophil Counts and Risk of Eosinophilic Granulomatosis with Polyangiitis Onset after Initiation of Dupilumab Administration in Adult Patients with Asthma.

Yoshitomo Kushima, Yasuo Shimizu, Hiromi Hoshi, Ryo Arai, Naoya Ikeda, Yusuke Nakamura, Meitetsu Masawa, Hiroaki Okutomi, Nana Yazawa, Kazuyuki Chibana, Akihiro Takemasa, Seiji Niho

Journal of clinical medicine（2023）

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摘要

Physicians should check for the onset of EGPA by monitoring the elevation of eosinophils within 6 months after dupilumab administration, especially in patients with PBE counts greater than 1500 cells/μL at 3 months.

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dupilumab,peripheral blood eosinophilia,eosinophilic granulomatosis with polyangiitis,asthma,rhinosinusitis

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