Vincristine-Induced Neuropathy in Patients Diagnosed with Solid and Hematological Malignancies: The Role of Dose Rounding.

Abdulrahman M Alwhaibi,Ali A Alshamrani,Miteb A Alenazi,Shroog F Altwalah,Nouf N Alameel,Noura N Aljabali,Sara B Alghamdi,Abdulwahab I Bineid,Monira Alwhaibi,Mohamed N Al Arifi

Journal of clinical medicine（2023）

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摘要

Our findings demonstrate that autonomic neuropathy is the most common vincristine-related neuropathy, regardless of the patient's age. Dose rounding is a significant determinant of vincristine-induced neuropathy in both groups. Further studies are needed to evaluate the variables that exacerbate or prevent neuropathy associated with the first-time use of vincristine.

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关键词

vincristine,neuropathy,dose rounding,cancer,solid tumors,hematologic malignancies

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