Spike Protein is a key target for stronger and more persistent T-Cell Responses - A study of mild and asymptomatic SARS-CoV-2 Infection.

Ivan Ssali,Susan Mugaba,Arthur Kalyebi Watelo, Juliana Bemanzi, Joseph Ssebwana Katende, Gerald Kevin Oluka, Violet Ankunda,Claire Baine,Laban Kato, Nathan Onyachi,Moses Muwanga,Mark Jjuuko,John Kayiwa,Christopher Nsereko, Betty Oliver Auma,Daniela Weiskopf,Alessandro Sette,Tom Lutalo,Monica Musenero,Pontiano Kaleebu,Jennifer Serwanga

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases（2023）

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摘要

This study highlights the dominant role of spike-directed T-cell responses in mild and asymptomatic disease and provides crucial longitudinal data from Sub-Saharan African settings. The findings provide valuable insights into the dynamics of T-cell responses and their potential significance in developing effective strategies for combating COVID-19.

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infection,t-cell,sars-cov

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