miR-200b-mediated reversion of a spectrum of epithelial to mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas.

Julia Illmer,Roland Zauner,Josefina Piñón Hofbauer,Monika Wimmer,Stefanie Gruner,Michael Ablinger,Johannes Bischof,Sonja Dorfer,Stefan Hainzl,Vanessa Tober,Shir Bergson,Ofer Sarig,Liat Samuelov,Christina Guttmann-Gruber,Ruby Shalom-Feuerstein,Eli Sprecher,Ulrich Koller,Martin Laimer, Johann W Bauer,Verena Wally

The British journal of dermatology（2023）

Cited 0|Views23

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Abstract

In summary, RDEB-SCCs exist in different EMT states and the level of miR-200b is indicative of how far an RDEB-SCC has gone down the EMT path. Moreover, reintroduction of miR-200b significantly reduced mesenchymal features.

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