Phase 1b safety and pharmacokinetics of intravenous and oral fosmanogepix in patients with acute myeloid leukaemia and neutropenia.
The Journal of antimicrobial chemotherapy(2023)
Abstract
Fosmanogepix was safe and well tolerated in AML patients with neutropenia receiving remission induction chemotherapy. Safety and PK profiles were comparable to healthy volunteers.
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Key words
acute myeloid leukaemia,oral fosmanogepix,pharmacokinetics,neutropenia
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