Chemical and oxidative properties of fine particulate matter from near-road traffic sources

The toxicity associated with the fine particulate matter (PM2.5) has not been well studied, particularly in relation to the emissions from on-road vehicles and other sources in low- and middle-income countries such as India. Thus, a study was conducted to examine the oxidative potential (OP) of PM2.5 at a roadside (RS) site with heavy vehicular traffic and an urban background (BG) site in Mumbai using the dithiothreitol (DTT) assay. Simultaneous gravimetric PM2.5 was measured at both sites and characterized for carbonaceous constituents and watersoluble trace elements and metals. Results depicted higher PM2.5, elemental carbon (EC), and organic carbon (OC) concentrations on the RS than BG (by a factor of 1.7, 4.6, and 1.2, respectively), while BG had higher watersoluble organic carbon (WSOC) levels (by a factor of 1.4) and a higher WSOC to OC ratio (86%), likely due to the dominance of secondary aerosol formation. In contrast, the measured OPDTTv at RS (8.9 +/- 5.5 nmol/min/m(3)) and BG (8.1 +/- 6.4 nmol/min/m(3)) sites were similar. However, OPDTTv at BG was higher during the afternoon, suggesting the influence of photochemical transformation on measured OPDTTv at BG. At RS, OC and redox-active metals (Cu, Zn, Mn, and Fe) were significantly associated with measured OP (p < 0.05), while at BG, WSOC was most strongly associated (p < 0.05). The coefficient of divergence (COD) for PM2.5, its chemical species, and OPDTTv was >0.2, indicating spatial heterogeneity between the sites, and differences in emission sources and toxicity. The estimated hazard index (HI) was not associated with OPDTTv, indicating that current PM2.5 mass regulations may not adequately capture the health effects of PM2.5. The study highlights the need for further studies examining PM2.5 toxicity and developing toxicity-based air quality regulations.