The low-density lipoprotein receptor fuels cholesterol-mTORC1 axis during CD8 T cell activation

F. Bonacina, A. Moregola, M. Svecla,A. Catapano,F. Marelli-Berg,G. Norata

Atherosclerosis（2023）

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摘要

Background and Aims: Activation of T lymphocytes combines functional to metabolic rewiring of cell machinery, including cholesterol homeostasis. Here we evaluated the role of LDLR, as a key regulator of cholesterol cellular uptake, on T cell biology.

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关键词

receptor,low-density,cholesterol-mtorc

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