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Effect of Statin Therapy on Coronary Inflammation Assessed by Pericoronary Adipose Tissue Computed Tomography Attenuation: Insights From the Multicentre Observational Study

K. Cheng, R. Hii,E. Lim,A. Lin,J. Yuvaraj,D. Dey,S. Nicholls,D. Wong

Heart, Lung and Circulation（2023）

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Abstract
Pericoronary adipose tissue (PCAT) attenuation quantified from routine computed tomography coronary angiography (CTCA) is a biomarker of coronary inflammation. However, the natural history of PCAT attenuation without intervention is unknown. High-intensity statin has a pleiotropic anti-inflammatory effect. This study assessed the temporal change of PCAT attenuation in patients with and without statin therapy.
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Key words
statin therapy,coronary inflammation,computed tomography
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