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Intra- and Interchromosomal Contact Mapping Reveals the Igh Locus Has Extensive Conformational Heterogeneity and Interacts with B-lineage Genes

Olga Mielczarek,Carolyn H. Rogers,Yinxiu Zhan,Louise S. Matheson,Michael J. T. Stubbington,Stefan Schoenfelder,Daniel J. Bolland,Biola M. Javierre,Steven W. Wingett,Csilla Varnai,Anne Segonds-Pichon,Simon J. Conn,Felix Krueger,Simon Andrews,Peter Fraser,Luca Giorgetti,Anne E. Corcoran

Cell Reports（2023）

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关键词
immunoglobin locus,Capture Hi-C,polymer modeling,3D immunoglobulin structure,genome organization,interchromosomal
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