Mutational landscape and predictors of survival in head and neck mucosal melanoma
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY（2024）
Abstract
Key PointsHead and neck mucosal melanomas have a diverse mutational landscape with low mutational burden.A molecular subset (& SIM;13%) has ROS1 mutations, which is an actionable driver mutation.ROS1-mutated patients have improved overall survival likely due to high mutational burden.
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Key words
mucosal melanoma,patient survival,tumor genetics,tumor mutational burden
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