Nimodipine Reduces Microvasospasms After Experimental Subarachnoid Hemorrhage.

Julian Schwarting,Biyan Nathanael Harapan,Xiangjiang Lin,Nikolaus Plesnila,Nicole A Terpolilli

Stroke（2023）

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摘要

Our results show that nimodipine reduces the formation of microvasospasms, thus, shedding new light on the mode of action of a drug routinely used for the treatment of SAH for >3 decades. Furthermore, L-type Ca2+ channels may be involved in the pathophysiology of microvasospasm formation.

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关键词

mice, microvessel, nimodipine, perfusion, spasm

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