Venous thromboembolism with use of hormonal contraception and non-steroidal anti-inflammatory drugs: nationwide cohort study.

Amani Meaidi,Annamaria Mascolo,Maurizio Sessa,Anne Pernille Toft-Petersen,Regitze Skals,Thomas Alexander Gerds,Charlotte Wessel Skovlund,Lina Steinrud Morch,Francesco Rossi,Annalisa Capuano,Oejvind Lidegaard,Christian Torp-Pedersen

BMJ (Clinical research ed.)（2023）

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摘要

NSAID use was positively associated with the development of venous thromboembolism in women of reproductive age. The number of extra venous thromboembolic events with NSAID use compared with non-use was significantly larger with concomitant use of high/medium risk hormonal contraception compared with concomitant use of low/no risk hormonal contraception. Women needing both hormonal contraception and regular use of NSAIDs should be advised accordingly.

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关键词

venous thromboembolism,hormonal contraception,nationwide cohort study,nationwide cohort,non-steroidal,anti-inflammatory

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