A randomized prospective comparative study between intrathecal chloroprocaine 1% and ropivacaine 0.5% for short duration surgery

ANAESTHESIA PAIN & INTENSIVE CARE(2023)

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摘要
Background and Objectives: Spinal anesthesia (SA) has recently seen a rapid surge in is popularity due to its edge over general anesthesia, being easier, cost-effective, lack of addictive drugs, reduced analgesic demand in the post anesthesia care unit, less nausea and vomiting within 24 h postoperatively, and a shorter hospital stay. Research continues regarding the best and the safest drug to be used for SA. We compared chloroprocaine 1% and ropivacaine 0.5% for SA in short duration surgery.Methodology: A total of 70 patient were enrolled and subdivided into two groups; Group R (35 patients), to receive 4 ml of 0.5 % ropivacaine (20 mg) and Group C (35 patients), to receive 4 ml of 1% chloroprocaine (40 mg). Hemodynamic parameters and block characteristics were compared between the two groups.Conclusion: This study shows that chloroprocaine 1% and ropivacaine 0.5% are equally effective in spinal anesthesia. However, chloroprocaine 1% is better suitable for shorter duration surgeries.
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关键词
Chloroprocaine, Ropivacaine, Hemodynamics, Block Characteristics
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