Molecular Biology teaching strategy for In Silico gene editing: A disruptive experience

In silico techniques are used to simulate experiments using molecular biology computational tools. This study aimed to promote the use of in silico assays in students of biotechnology engineering at the Universidad Regional Amazonica Ikiam. The methodology consisted of three phases: a) planning and organization, b) practice and execution, and c) project evaluation. In this sense, each group used bibliographic sources indexed in Scopus, Springer, and PubMed; databases such as Bioweb and Genbank; genome banks AddGene, EMBL, and NCBI; to assemble a new plasmid in Benchling. The main result was six projects that sought alternatives to current health, environmental, and agricultural challenges. Among the projects linked to health, there were two projects, G- 1 and G-2, while the projects focused on the environmental component, G-4 and G-5, and those related to agricultural improvement, G-3, and G-6. According to the surveyconducted at the end of the semester, the classroomprojects were highly accepted. It is suggested thatthese strategies be utilized when studying topics associated with the biological sciences.