GC-MS analysis and isolation of few bioactive phytoconstituents from Ixora parviflora Lam.

Ixora parviflora Lam. is a small garden tree which is very well known for its medicinal properties and health benefits as mentioned in Ayurveda and Siddha system of medicine. In spite of many uses of the plant, there is no much research done and only a few compounds were isolated from the plant. This article main aim is to present the extensive research work carried out on this plant for characterization and isolation of phytoconstituents. Hexane, ethyl acetate and methanol extracts were analysed by GC-MS to investigate the active components in the plant. After successive extraction of the leaves, the crude methanolic extract of the leaves was subjected to column chromatography for the isolation of compounds using various solvent systems and they were characterized using spectroscopic techniques like NMR, FTIR and mass for elucidation of the structures. Seven compounds were isolated and some of them are being reported for the first time in the plant such as oleanolic acid, betulinic acid, caffeic acid and gallic acid. Apigenin and chlorogenic acid are being reported first time in leaf. They were earlier reported in flowers of this plant. Betulin which was reported earlier was also isolated. The isolation of phytoconstituents is overriding to make the treatment of diseases or disorders easy and is a foremost step in new drug development process.