A neonatal lupus syndrome with pericardial tamponade due to maternal Sjogren's syndrome

Neonatal lupus syndrome (NLS) is a rare disease with dermatological, cardiac, hepatic and hematologic involvement due to placental transfer of anti-Ro/ SSA and anti-La/ SSB antibodies in infants of mothers with autoimmune diseases. Multisystemic involvement is common in infants. Here we present a baby with neonatal lupus syndrome whose mother had Sjögren's syndrome. He presented with thrombocytopenia, then convulsion and cardiac arrest due to pericardial tamponade. So, the risk of NLS should be kept in mind in infants of mothers with autoimmune diseases.