Two New Phenolic Glycosides from Thalictrum scabrifolium and Their Anti-TMV Activities

CHEMISTRY OF NATURAL COMPOUNDS(2023)

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摘要
Two new phenolic glycosides, 2-(2-((1E,6Z)-3,8-dihydroxy-3,7-dimethylocta-1,6-dien-1-yl)-4-hydroxy-6-methylphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol ( 1 ) and 2-(2-((E)-2-(2,6-dimethyl-2,3,4,7-tetrahydrooxepin-2-yl)vinyl)-4-hydroxy-6-methylphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol ( 2 ) were isolated from Thalictrum scabrifolium . Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited anti-TMV activities with inhibition rates of 34.1 and 35.9% at a concentration of 20 μM/mL, respectively, compared with 35.3% for the positive control ningnanmycin.
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关键词
Thalictrum scabrifolium,phenolic glycoside,anti-TMV activity
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