Demonstrating the feasibility of a novel solar photo-Fenton strategy for full-scale operationalization according to EU 2020/741 disinfection targets for water reuse

•Supply of Fe3+-NTA, H2O2 and NaOCl was evaluated against all EU 2020/741 indicators.•Chlorination was the primary factor in bacteria and viruses’ inactivation.•Solar photo-Fenton mediated by Fe3+-NTA presented limited results, except for MS2.•This approach has proceeded to reduce E. coli, TC, E. faecalis and MS2 load.•Enhance oxidation conditions are required to attain C. perfringens inactivation.