Residue analysis, dissipation dynamics, and dietary risk assessment of benzovindiflupyr in peanut field environment by LC-MS

Benzovindiflupyr is a succinate dehydrogenase inhibitor fungicide, and its residues in the environment could pose a threat to ecological safety. The aim of this study was to develop a method for determining benzovindi-flupyr residues in peanut fields and to perform residue dissipation, final residue analysis, and dietary risk assessment. The samples were extracted with acetonitrile, cleaned up using MWCNTs, and detected by HPLC-MS. The results showed that the concentrations and peak areas of benzovindiflupyr showed a good linear correlation (R2 >0.99) in a certain concentration range, and the LOD and LOQ values ranged from 0.001 to 0.002 mg/kg and 0.004-0.008 mg/kg, respectively. The average intra-day and inter-day recovery rates of benzovindiflupyr from four blank matrices spiked at 0.01, 0.04 and 0.1 mg/kg ranged from 82.4% to 101% with a RSDr of 0.790-9.36%, and 83.6-98.7% with a RSDR of 1.61-7.24%, respectively. The dissipation half-lives of benzovindiflupyr in field soil and peanut plants were 8.53-8.56 days and 14.9-17.3 days, respectively. The residual benzovindiflupyr in peanut kernels poses no health risk to Chinese consumers. These findings can help guide the application of benzovindiflupyr in the peanut field environment and minimize the environmental risks associated with its use.